Thymosin Alpha-1

Peptide Name: Thymosin Alpha 1 
CAS Number: 62304-98-7
 
General Overview
Thymosin Alpha 1 is a potent 28-amino acid peptide naturally occurring in the thymus gland. It is a critical pleiotropic hormone responsible for the restoration of immune homeostasis. Research into its synthetic form, often referred to as Thymalfasin, focuses on its ability to act as a biological response modifier. Unlike immunosuppressants, T$\alpha$1 is studied for its dual-action capability: it can stimulate an underactive immune system to fight infections or cancer, while simultaneously modulating an overactive immune response to prevent tissue damage from excessive inflammation.
 
Researched Benefits
T-Cell Differentiation: Studies indicate that T$\alpha$1 significantly increases the production and maturation of T-lymphocytes, specifically improving the CD4+/CD8+ ratio in immunocompromised models.
Pathogen Neutralization: Extensively researched for its efficacy against chronic viral infections such as Hepatitis B and C, as well as its role in mitigating severe symptoms of respiratory viruses.
Anti-Tumor Activity: Research suggests it enhances the expression of Major Histocompatibility Complex (MHC) class I molecules on tumor cells, making them more "visible" to the immune system.
Reduction of Cytokine Storms: In trials involving acute inflammation and sepsis, T$\alpha$1 has shown a capacity to inhibit the release of pro-inflammatory cytokines like IL-6 and TNF-$\alpha$.
Neuroprotection and Anti-Aging: Emerging research in 2026 explores its potential to counteract "immunosenescence"—the natural decline of the immune system due to age-related thymic involution.
 
KIT INCLUDES:
1x Peptide Vial
1x 10ml Sterile Water
1x Reconstitution Kit
 
Disclaimers
SAHPRA DISCLAIMER: This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA). This product is not intended to diagnose, treat, cure, or prevent any disease.
RESEARCH USE ONLY: This compound is strictly for research and development purposes only. 
 
Research Studies and References
Thymosin Alpha 1: Biological Activities and Applications (2024 Review): https://pmc.ncbi.nlm.nih.gov/articles/PMC7115394/
Safety and Efficacy of T$\alpha$1 in Human Clinical Trials (2024 Meta-analysis): https://www.researchgate.net/publication/377955726_Comprehensive_Review_of_the_Safety_and_Efficacy_of_Thymosin_Alpha_1_in_Human_Clinical_Trials
Thymosin Alpha 1 Mitigates Cytokine Storm (Oxford Academic): https://academic.oup.com/ofid/article/8/1/ofaa588/6024458
The Role of T$\alpha$1 in Viral Infectious Diseases (MDPI 2023): https://www.mdpi.com/1420-3049/28/8/3539
Aging and Thymosin Alpha-1 (2025/2026 Update): https://www.mdpi.com/1422-0067/26/23/11470