KPV

PRODUCT DESCRIPTION
Peptide Name: KPV
 
Intestinal inflammation reduced significantly
Skin disorders treatment potential
Antimicrobial properties highly effective
Immune system signaling modulated
Wound healing recovery accelerated
 
Chemical Name: (2S)-2-[[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoic acid
CAS Number: 67727-97-3
 
GENERAL DESCRIPTION
KPV is a potent naturally occurring tripeptide consisting of the amino acids Lysine, Proline, and Valine. It is a C-terminal fragment derived from the alpha-Melanocyte-Stimulating Hormone (alpha-MSH). Unlike its parent molecule, KPV does not induce skin pigmentation, making it a highly specific subject for research into anti-inflammatory and anti-microbial pathways without hormonal side effects.
Anti-Inflammatory Action: Research indicates KPV functions by entering cells and inactivating the NF-kappaB signaling pathway, which is a primary driver of chronic inflammation.
Gastrointestinal Support: Studies focused on Inflammatory Bowel Disease (IBD) suggest that KPV can be transported into the gut via the PepT1 transporter, potentially reducing colonic inflammation and restoring the mucosal barrier.
Dermatological Applications: In vitro and in vivo studies have explored its ability to reduce redness, swelling, and itching associated with conditions like psoriasis and eczema.
Anti-Microbial Activity: The peptide has shown the ability to disrupt the cell walls of certain pathogens, including bacteria and fungi like Candida albicans.
 
KIT INCLUDES:
1x Peptide Vial
1x 10ml Sterile Water
1x Reconstitution Kit
 
SAHPRA DISCLAIMER AND USAGE
This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA). This product is not intended to diagnose, treat, cure, or prevent any disease.
RESEARCH USE ONLY. Not for human consumption or diagnostic use.
 
RESEARCH STUDIES AND LINKS
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation: https://pmc.ncbi.nlm.nih.gov/articles/PMC2431115/
Alpha-Melanocyte-Stimulating Hormone and Related Tripeptides: Biochemistry and Anti-inflammatory Effects: https://academic.oup.com/edrv/article/29/5/581/2355042
KPV Peptide Delivery and Recent Advances in Research: https://www.scitechnol.com/peer-review/recent-advances-in-kpv-peptidedelivery-8OYD.php?article_id=18216
The Melanocortin System in Inflammatory Bowel Diseases: https://www.mdpi.com/2073-4409/12/14/1889