Kisspeptin-10
PRODUCT DESCRIPTION
Peptide Name: Kisspeptin (Kisspeptin-10)
RESEARCHED AREAS AND BENEFITS
GnRH stimulation restores fertility
LH pulse frequency increase
HSDD treatment boosts desire
Melanoma metastasis growth inhibition
Puberty onset regulation signaling
Chemical Name: L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-phenylalaninamide
CAS Number: 374675-21-5
DESCRIPTION
Kisspeptin is a naturally occurring peptide hormone encoded by the KISS1 gene and was originally identified as "metastin" due to its ability to suppress cancer metastasis. In neuroendocrinology, it is recognized as the primary upstream regulator of the reproductive axis, acting directly on GnRH neurons in the hypothalamus. Kisspeptin-10 is the shortest biologically active fragment of the full-length 145-amino acid protein and is widely used in research to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Its role is central to the initiation of puberty and the maintenance of adult reproductive function.
Reproductive Axis Control: Research shows it is the most potent stimulator of the hypothalamic-pituitary-gonadal (HPG) axis.
Libido and Arousal: Clinical studies indicate that kisspeptin enhances brain pathways associated with sexual attraction and can increase penile rigidity.
Fertility Restoration: Investigations suggest potential for treating hypothalamic amenorrhea and other forms of hypogonadotropic hypogonadism.
Oncology Research: Studies continue to explore its anti-metastatic properties, particularly in melanoma and breast cancer cell lines.
KIT INCLUDES:
1x Peptide Vial
1x 10ml Sterile Water
1x Reconstitution Kit
REGULATORY NOTICES
SAHPRA DISCLAIMER This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA). It is not intended to diagnose, treat, cure, or prevent any disease.
RESEARCH USE ONLY
SCIENTIFIC STUDIES
Kisspeptin-10 Is a Potent Stimulator of LH and Increases Pulse Frequency in Men: https://pmc.ncbi.nlm.nih.gov/articles/PMC3380939/
Kisspeptin hormone injection could treat low sex drive in women and men: https://www.imperial.ac.uk/news/242901/kisspeptin-hormone-injection-could-treat-drive/
Advances in clinical applications of kisspeptin-GnRH pathway in female reproduction: https://pmc.ncbi.nlm.nih.gov/articles/PMC9125910/
Kisspeptin and the control of emotions, mood and reproductive behaviour: https://joe.bioscientifica.com/view/journals/joe/239/1/JOE-18-0269.xml

















