Epithalon

PEPTIDE NAME: Epithalon
CHEMICAL NAME: L-alanyl-L-alpha-glutamyl-L-alpha-aspartylglycine
CAS NUMBER: 307297-39-8
 
DESCRIPTION
Epithalon (also known as Epitalon or AEDG) is a synthetic tetrapeptide derived from Epithalamin, a natural polypeptide secreted by the pineal gland. It was originally developed by the St. Petersburg Institute of Bioregulation and Gerontology to study the mechanisms of cellular aging and organ function restoration. Research primarily focuses on its ability to interact with DNA and modulate the production of specific enzymes and hormones that typically decline with age.
 
RESEARCHED BENEFITS
Telomerase Activation: Research indicates the peptide may activate the enzyme telomerase, which helps maintain and elongate telomeres, potentially delaying cellular senescence.
Circadian Rhythm Regulation: Studies suggest it can stimulate the production of endogenous melatonin, helping to restore normal sleep-wake cycles in aged models.
Oncostatic Properties: Investigations in animal models have shown a potential reduction in the development of spontaneous tumors and metastases.
Neuroprotection: Experimental data points to improved synaptic plasticity and neurogenic differentiation in stem cell research.
Visual Health: Research in patients with retinal degeneration suggests the peptide may help preserve the functional integrity of the retina.
 
KIT INCLUDES:
1x Peptide Vial
1x 10ml Sterile Water
1x Reconstitution Kit
 
SAHPRA DISCLAIMER AND RESEARCH USE ONLY
DISCLAIMER: THIS PRODUCT HAS NOT BEEN EVALUATED BY THE SOUTH AFRICAN HEALTH PRODUCTS REGULATORY AUTHORITY (SAHPRA) FOR SAFETY, QUALITY, OR INTENDED USE.
RESEARCH USE ONLY
 
RESEARCH STUDIES
https://pubmed.ncbi.nlm.nih.gov/12374906/
https://pmc.ncbi.nlm.nih.gov/articles/PMC11943447/
https://www.mdpi.com/1420-3049/25/3/609
https://pubmed.ncbi.nlm.nih.gov/11883301/