LL-37

LL-37 (CATHELICIDIN)
 
RESEARCH SNAPSHOT
Potent antimicrobial defense mechanism
Inflammatory response modulation activity
Rapid epithelial wound closure
Angiogenesis and vessel formation
Biofilm disruption research applications
 
PRODUCT DESCRIPTION
Peptide Name: LL-37
Chemical Name: Cathelicidin antimicrobial peptide (human)
CAS Number: 154945-66-9
 
LL-37 is a 37-amino acid linear peptide that serves as a critical component of the innate immune system. It is the only member of the cathelicidin family found in humans, typically released by epithelial cells and white blood cells. Its unique amphipathic alpha-helical structure allows it to interact directly with microbial membranes. Beyond its direct defense properties, LL-37 is extensively researched for its multifaceted role as a signaling molecule that bridges innate and adaptive immunity.
Broad-Spectrum Activity: Researched for its ability to neutralize bacteria, fungi, and certain viruses.
Wound Repair: Investigations show it may recruit cells necessary for tissue repair and re-epithelialization.
Immune Regulation: Studies explore how it balances the inflammatory response to prevent tissue damage.
Pathogen Interference: It is used in studies focused on breaking down protective bacterial biofilms.
 
DISCLAIMER
SAHPRA DISCLAIMER: This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA). This product is not intended to diagnose, treat, cure, or prevent any disease.
FOR RESEARCH USE ONLY.
 
RESEARCH LINKS
https://pubmed.ncbi.nlm.nih.gov/22415303/
https://www.frontiersin.org/articles/10.3389/fimmu.2019.01153/full