IGF-1 LR3

Peptide Name: IGF-1 LR3
 
Inducing skeletal muscle hyperplasia.
Stimulating systemic protein synthesis.
Improving connective tissue recovery.
Regulating glucose transport mechanisms.
 
(Long Arginine 3-Insulin-like Growth Factor-I)   Chemical Name: [Arg3] insulin-like growth factor I (human) lengthened at the N-terminus by a 13-residue extension peptide
 
 
CAS Number: 946870-92-4  
 
DESCRIPTION
IGF-1 LR3 is a synthetic, 83-amino acid analog of human IGF-1. It differs from the native hormone by the substitution of an Arginine for Glutamic Acid at position 3 and the addition of a 13-amino acid extension peptide at the N-terminus. These modifications significantly decrease the peptide's affinity for IGF-binding proteins (IGFBPs). This results in a much higher metabolic stability and a significantly longer half-life (approximately 20–30 hours compared to the 20-minute half-life of standard IGF-1), making it a potent subject for research into cellular growth and tissue repair.
Hyperplasia Support: Research indicates it may promote the division and proliferation of new muscle cells (hyperplasia) rather than just the enlargement of existing ones.
Enhanced Nutrient Shuttling: Studies show it increases the transport of amino acids and glucose into muscle cells, potentially improving recovery and glycogen replenishment.
Tissue Repair: Laboratory investigations highlight its role in stimulating collagen synthesis and repairing connective tissues, tendons, and ligaments.
Muscle Maintenance: Preliminary data suggests it can inhibit muscle protein breakdown and counteract muscle wasting in clinical research models.
 
KIT INCLUDES:
1x Peptide Vial
1x 10ml Sterile Water/Bacteriostatic Water
1x Reconstitution Kit
 
REGULATORY NOTICES
SAHPRA DISCLAIMER This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA). It is not intended to diagnose, treat, cure, or prevent any disease. RESEARCH USE ONLY
 
SCIENTIFIC STUDIES
Structural and Functional Properties of Long R3 IGF-1: https://pubmed.ncbi.nlm.nih.gov/8432095/
IGF-1 and Muscle Growth Mechanisms: https://pmc.ncbi.nlm.nih.gov/articles/PMC3311440/
The Role of IGF-1 LR3 in Proliferation and Differentiation: https://pubmed.ncbi.nlm.nih.gov/11472111/
Impact of IGF-1 Analogs on Protein Synthesis: https://pubmed.ncbi.nlm.nih.gov/1653135/