RESEARCH NOTICE & LEGAL DISCLAIMER

FOR RESEARCH PURPOSES ONLY. All information provided within the Biolabs Peptides Research Centre is intended strictly for scientific, laboratory, and educational purposes.

Not Medical Advice: The protocols and data presented herein do not constitute medical advice, nursing advice, or a professional healthcare diagnosis.
Non-Therapeutic: These peptides are not intended to diagnose, treat, cure, or prevent any medical condition or disease.
Researcher Responsibility: Any research conducted should be performed by qualified professionals in a controlled laboratory environment. By accessing this data, you acknowledge that you are responsible for following your local laws and institutional safety guidelines.

MOTS-C
(10mg)(40MG)

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HIGHLIGHTS

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a 16-amino-acid peptide that represents a breakthrough in mitochondrial-derived research. Often called an "exercise mimetic," MOTS-c acts as a potent metabolic regulator by activating the AMPK (AMP-activated protein kinase) pathway. In research models, it is studied for its ability to enhance insulin sensitivity, promote fat oxidation, and increase physical endurance. By signaling from the mitochondria to the nucleus, MOTS-c helps maintain metabolic homeostasis and counters age-related physical decline, making it a primary focus for longevity and metabolic syndrome studies.

Observed Benefits

AMPK Activation: Mimics the cellular effects of exercise by stimulating energy-efficient pathways.
Insulin Sensitivity: Observed to enhance glucose uptake and reduce insulin resistance in research models.
Fat Oxidation: Studied for its role in preventing diet-induced obesity by accelerating the breakdown of fatty acids.
Mitochondrial Health: Promotes the survival of cells under metabolic stress and supports mitochondrial biogenesis.
Physical Capacity: Linked to significant improvements in treadmill running time and muscle homeostasis in older research subjects.

Protocol Overview

MOTS-c research utilizes daily subcutaneous administration. To maintain measurement consistency in South African laboratories, both the 10mg and 40mg vials are reconstituted with 3.0 mL of Bacteriostatic Water.

Research Protocol Dosing

Concentration Reference:

10mg Vial (3.0 mL): ~3.33 mg per mL.
40mg Vial (3.0 mL): ~13.33 mg per mL.

The following measurements provide the required units on a U-100 insulin syringe for a daily administration schedule.

Weeks 1–2: Initial Assessment (200 mcg Daily)

10mg Vial: 6 units on a U-100 syringe.
40mg Vial: 1.5 units on a U-100 syringe.

Weeks 3–4: Escalation (400 mcg Daily)

10mg Vial: 12 units on a U-100 syringe.
40mg Vial: 3 units on a U-100 syringe.

Weeks 5–6: Intermediate (600 mcg Daily)

10mg Vial: 18 units on a U-100 syringe.
40mg Vial: 4.5 units on a U-100 syringe.

Weeks 7–8: High Dose (800 mcg Daily)

10mg Vial: 24 units on a U-100 syringe.
40mg Vial: 6 units on a U-100 syringe.

Weeks 9–10+: Target Efficacy (1,000 mcg / 1 mg Daily)

10mg Vial: 30 units on a U-100 syringe.
40mg Vial: 7.5 units on a U-100 syringe.

Supplies Needed

Biolabs Peptides MOTS-c: 10mg or 40mg Lyophilized Vial.
Reconstitution Liquid: 3.0 mL of Bacteriostatic Water.
Syringes: U-100 Precision Insulin Syringes (0.3 mL, 0.5 mL, or 1.0 mL).
Prep: Sterile alcohol swabs for vial and site sterilization.

Storage

Pre-reconstitution (Lyophilized Powder): Store frozen at -20°C (-4°F) for maximum long-term stability. Protect from UV light.
Post-reconstitution (Liquid Solution): Must be refrigerated at 2–8°C (36–46°F). MOTS-c is highly sensitive; for peak research integrity, the solution should be used within 30 Days of reconstitution. Do not freeze the liquid.
Handling: Never shake the vial; gently swirl or roll to dissolve the powder into the solution.