KPV (Lysine-Proline-Valine) 10 mg Vial: Dosage Protocol (3 mL Dilution)

KPV is a tripeptide researched for its potent anti-inflammatory properties, particularly concerning gut health and systemic inflammation. Using a larger volume of diluent (3.0 mL) allows for more precise measurement of these smaller microgram doses.

1. Reconstitution (Mixing)

• Diluent: Add 3.0 mL of Bacteriostatic Water to your 10 mg vial.

• Concentration: This creates a 3.33 mg/mL solution.

• Measurement: On a standard U-100 (1 mL) insulin syringe, 1 unit = 33.33 mcg.

Reconstitution Steps:

1. Draw 3.0 mL of bacteriostatic water into a sterile syringe.

2. Inject the water slowly down the inside wall of the vial to avoid foaming.

3. Gently swirl or roll the vial between your hands until the powder is fully dissolved. Do not shake.

4. Label the vial and store it in the refrigerator.

2. The Titration Schedule

(Doses are administered via subcutaneous injection once daily)

Week 1: Initiation

• Daily Dose: 200 mcg

• Syringe Volume: 6 Units (0.06 mL)

Week 2: Escalation

• Daily Dose: 300 mcg

• Syringe Volume: 9 Units (0.09 mL)

Week 3: Escalation

• Daily Dose: 400 mcg

• Syringe Volume: 12 Units (0.12 mL)

Weeks 4–8: Maintenance

• Daily Dose: 500 mcg

• Syringe Volume: 15 Units (0.15 mL)

3. Administration & Storage

• Method: Subcutaneous injection into the fatty tissue of the abdomen or thigh.

• Precision Tip: For doses under 10 units, consider using a 30-unit (0.3 mL) or 50-unit (0.5 mL) insulin syringe for easier readability and more accurate measurement.

• Storage: * Unopened Vials: Store in the freezer at -20°C.

  • Reconstituted Vials: Store in the refrigerator (2°C – 8°C) and protect from light. Use within 30 days.

4. Side Effects & Management

• Common Effects: KPV is generally well-tolerated in research, though mild redness or irritation at the injection site may occur.

• Hydration: Maintain consistent water intake to support the body's natural inflammatory response.

SAHPRA COMPLIANCE & LEGAL DISCLAIMER

ATTENTION: This product is NOT REGISTERED with the South African Health Products Regulatory Authority (SAHPRA).

1. This medicine has not been evaluated by SAHPRA for its quality, safety, or intended use.

2. KPV is currently an investigational compound and is not approved for the treatment of any medical condition in South Africa.

3. In terms of the Medicines and Related Substances Act (Act 101 of 1965), the use of unregistered medicines is generally restricted to authorized clinical trials or specific Section 21 authorizations.

4. WARNING: Compounded or unregistered peptides have been flagged by SAHPRA as potentially "undesirable" due to risks of contamination, incorrect dosing, and lack of sterile oversight. Use of this substance is at the user’s own risk. Consult a registered medical practitioner before use.

Medical Notice: This document is for informational purposes only and does not replace professional medical advice. If you experience any adverse reactions, discontinue use and seek immediate medical attention.